At Epetōme, we are dedicated to delivering the pinnacle of digestive health support through our innovative synbiotic duo cap. Our product is the result of rigorous scientific development and collaboration with leading scientists and manufacturers, led by the vision of nutritionist Emily English, ensuring the highest quality and efficacy in one daily dosage.
what you can expect:
potency.
50 billion colony-forming units (CFU); one of the highest counts on the market.
efficacy.
Designed with an inner core and outer shell to ensure the bacteria withstand the harsh conditions of your GI tract and reach the gut alive.
dIversity.
11 clinically trialled bacterial strains spanning 7 different species. Read more on our strain taxonomy below.
convenience.
One capsule - just once a day, every day. No gimmicks, no refrigeration, no blending. Just take as you hydrate first thing in the morning.
Read on to learn more about the intricacies of the synbiotic duo cap.
Emily English is a BSC qualified nutritionist. Her understanding of digestive wellness has helped thousands of people who want a better relationship with their gut. It is Emily’s mission to demystify complex health concepts, promoting a vision of health that is simple, liberating and joyful.
Our synbiotic duo cap. is a blend of science and nature, meticulously formulated to harness 11 strains of purposefully chosen bacteria across 7 species.
Our strain taxonomy consists of strains with extensive mechanistic and clinical data generated at academic institutions and researchers around the world. Over 450 studies have been conducted on our strains over a 46 year period, exploring hypotheses across digestion, immunity, skin, cognition and hormones. This careful selection came from the desire to create an all-round health solution that complements you and your unique microbiome.
Further, we ensure that the full dosage of live and active bacteria is delivered at or above label claim throughout the entire shelf life, with the addition of advanced encapsulation technology that allows for unparalleled delivery to your gut.
Epetōme's synbiotic duo cap. includes state-of-the-art encapsulation; developed with an outer shell and inner core, to ensure targeted delivery of ingredients within the gut, where the microbiome thrives.
The transparent outer shell is designed to break down in your stomach, releasing fructooligosaccharides (FOS) fibre, which act as food for the live bacteria. It also contains Vitamin D3, Biotin and Zinc, all of which have been included for their role in supporting a healthy gut.
Not visible to the naked eye, within the green inner capsule are 50 billion live bacteria. Protected by the outer shell as it makes its way through the stomach, this inner capsule is able to continue through the gastro-intestinal tract, breaking down in the intestines and releasing the live cultures into your gut microbiome.
SHIME® testing, or Simulator of the Human Intestinal Microbial Ecosystem, is a sophisticated in vitro technology that simulates the human gastrointestinal tract. It is used to study the impact of products like our duo cap on the microbiome. You may not have heard of SHIME® from many other supplement brands, as the rigorous process can quickly expose the flaws in bacterial delivery systems.
The lab team simulated how the duo cap behaves in real-world conditions, with results demonstrating that the capsule technology is 30x more effective than a standard capsule in ensuring the bacteria make it to the gut in an active state.
For Epetōme, utilising SHIME® testing to validate the efficacy of the duo cap underscores a commitment to scientific excellence and consumer benefit. SHIME® testing demonstrates the survivability and targeted delivery of our capsule through the harsh conditions of the stomach to reach the intestines, where these components can add to the diversity and complement the gut microbiome.
Our capsule takes intricate health science and transforms it into one simple daily ritual, making optimal gut health an accessible goal for everyone.
Our capsule takes intricate health science and transforms it into one simple daily ritual, making optimal gut health an accessible goal for everyone.
Our capsule contains 11 unique bacterial strains from 7 different species. They have each been carefully selected for the scientific and mechanistic research behind them. Amongst them, we are proud to include Lactobacillus acidophilus NCFM, the world's most researched strain of acidophilus especially trialled for IBS-related pain and bloating.
If you love to explore the science behind your supplements, our research library contains extensive detail on over 450 studies behind the synbiotic duo cap.'s ingredients.
The Role of Probiotics in Improving Gut Health in Healthy Volunteers with Evacuation Disorders and Hard Stools. Journal of Clinical Gastroenterology, 44(Suppl 1), S30-S34.
A New Chance of Preventing Winter Diseases by the Administration of Symbiotic Formulations.Journal of Clinical Gastroenterology, 42(2), 224-233.
Efficacy of probiotic supplementation for constipation relief.International Journal of Gastroenterology and Hepatology, 59(1), 15-19.
Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial.Journal of Clinical Immunology, 28(6), 542-551.
Modulatory effects of Lactiplantibacillus plantarum on chronic metabolic diseases.Food Science and Human Wellness.
Lactobacillus rhamnosus GG: a review of clinical use and efficacy. Nutr. Med. J., 1(3), 70-116.
Supplementation with Bifidobacterium breve BR03 and B632 strains improved insulin sensitivity in children and adolescents with obesity in a cross-over, randomized double-blind placebo-controlled trial. Clinical Nutrition, 40(7), 4585-4594.
Probiotics and fructo-oligosaccharide intervention modulate the microbiota-gut brain axis to improve autism spectrum reducing also the hyper-serotonergic state and the dopamine metabolism disorder.
Fecal recovery of probiotics administered as a multi-strain formulation during antibiotic treatment.
A randomised controlled trial of a probiotic and a prebiotic examining metabolic and mental health outcomes in adults with pre-diabetes. BMJ Open, 12:e055214.
Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50(3):e13201.
Probiotic Supplementation for Rheumatoid Arthritis: A Promising Adjuvant Therapy in the Gut Microbiome Era. Front. Pharmacol., 12:711788.
Lactobacillus plantarum: A Potential Health Booster - A Comprehensive Review.
The use of probiotics in the treatment of constipation in the elderly.
Role of D-Mannose in the Prevention of Recurrent Uncomplicated Cystitis: State of the Art and Future Perspectives. Antibiotics, 10, 373.
Fructooligosaccharides (FOS) act as the food and energy source for the live bacteria in our capsule. Housed within the liquid layer, it is released first to support the function of the live inner core.
READ MORE ON FOS
Our daily choices - what we eat, our stress levels, sleep patterns, and even our physical activity - can significantly impact the balance of our gut.
