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synbiotic duo cap.
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just once a day, every day.

Access your gut's potential. 50 billion CFU. 11 clinically trialled bacterial strains. Advanced encapsulation technology. Best taken daily over a minimum of 3 months.

One-Time Purchase
1 month supply (Trial Pack)
30 servings
£54.99
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Free delivery on all UK orders over £40.
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90 day money-back guarantee.
your unique journey.
Your microbiome is as unique as you are - it's as unique as your fingerprint. Therefore, your journey will be unique to you too. Here's what you may expect, with some variance to be expected.
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Day 0
Your new daily habit starts. Remember, just once a day, every day.
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Week 1
Your body starts getting acquainted with its new guests.
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Month 1
You have cemented your new routine, with some fluctuations still possible.
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Month 3
Your body starts to adapt, finding tempo and balance.
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Month 6
Personal discoveries? We’d love to hear them.
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optimised by technology.

Epetōme's synbiotic duo cap. is the meeting point of science and simplicity. 30x more effective than a standard capsule, its unique capsule-in-capsule design ensures targeted delivery of ingredients within the gut, where the microbiome thrives.

inner outer

The transparent outer shell is designed to break down in your stomach, releasing fructooligosaccharides (FOS) fibre, which act as food for the live bacteria. It also contains Vitamin D3, Biotin and Zinc, all of which have been included for their role in supporting a healthy gut.

outer

Not visible to the naked eye, within the green inner capsule are 50 billion live bacteria. Protected by the outer shell as it makes its way through the stomach, this inner capsule is able to continue through the gastro-intestinal tract, breaking down in the intestines and releasing the live cultures into your gut microbiome.

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designed to reach the gut alive.

The 50 billion bacteria within the synbiotic duo cap. are live organisms. Therefore, it is essential that they are protected as they pass through the harsh conditions of your gastrointestinal (GI) tract. Our capsule technology has been tested using the most accurate recreation of the digestive system, SHIME®, to prove that all bacteria make it to the gut alive.

LEARN MORE
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Utilising a cutting-edge testing method that mimics the human gastrointestinal tract, the Lab Team simulated how the duo cap behaves in real-world conditions.
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Simulator of the Human Intestinal Microbial Ecosystem (SHIME®)
11
clinically trialled bacterial strains.
50 billion
colony forming units.
30x
more effective than a standard capsule.
emily english explores the synbiotic duo cap's unique bacterial composition.
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helping you to look after your gut.

Our capsule takes intricate health science and transforms it into one simple daily ritual, making optimal gut health an accessible goal for everyone.

helping you to look after your gut.

Our capsule takes intricate health science and transforms it into one simple daily ritual, making optimal gut health an accessible goal for everyone.

The importance of a healthy gut microbiome.

Our gut bacteria play an incredibly complex and critical role in helping us thrive. The microbiome affects everything from digestion to the immune system, hormones, skin health and even mental wellbeing.

MIND
SKIN
IMMUNITY
DIGESTION
HORMONES
our unique formulation.

Our capsule contains 11 unique bacterial strains from 7 different species. They have each been carefully selected and are all trademarked and registered. In amongst them, we are proud to include Lactobacillus acidophilus NCFM, the world's most researched strain of acidophilus.


Paired with FOS fibre and key nutrients, all contained within our state-of-the-art duo cap, we ensure the targeted delivery of ingredients to the right place, at the right time. 

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15 active ingredients.
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Fructooligosaccharides (FOS) act as the food and energy source for the live bacteria in our capsule. Housed within the liquid layer, it is released first to support the function of the live inner core.

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Bifidobacterium lactis BS01
12.88 billion CFU
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This particular bifidobacterium has many clinical trials exploring its ability to help with digestive issues like constipation.
View Studies
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Del Piano, M., Carmagnola, S., Anderloni, A., et al. (2010).

The Role of Probiotics in Improving Gut Health in Healthy Volunteers with Evacuation Disorders and Hard Stools. Journal of Clinical Gastroenterology, 44(Suppl 1), S30-S34.

Pregliasco, F., Anselmi, G., Fonte, L., Giussani, F., Schieppati, S., Soletti, L. (2008).

A New Chance of Preventing Winter Diseases by the Administration of Symbiotic Formulations. Journal of Clinical Gastroenterology, 42(2), 224-233.

Lactobacillus acidophilus NCFM
10 billion CFU
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We are proud to include the world's most researched strain of acidophilus. Many studies explore its link with IBS-related pain, bloating, immune support, cognition and skin health.
View Studies
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Magro, D.O., de Oliveira, L.M., Bernasconi, I., et al. (2014).

Efficacy of probiotic supplementation for constipation relief.International Journal of Gastroenterology and Hepatology, 59(1), 15-19.

Paineau, D., Carcano, D., Leyer, G., et al. (2008).

Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial.Journal of Clinical Immunology, 28(6), 542-551.

Lactobacillus plantarum LP-115
8 billion CFU
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LP-115 has been tested on its potential to promote beneficial effects in the immune system and alleviate intestinal disorders.
View Studies
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Tian, L., Zhao, R., Xu, X. et al. 2023.

Modulatory effects of Lactiplantibacillus plantarum on chronic metabolic diseases. Food Science and Human Wellness.

Lactobacillus rhamnosus GG
7.11 billion CFU
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Lactobacillus rhamnosus GG appears in trials on conditions such as diarrhea, inflammatory bowel disease, atopic dermatitis, and even dental caries.
View Studies
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Steele, C. (2022).

Lactobacillus rhamnosus GG: a review of clinical use and efficacy. Nutr. Med. J., 1(3), 70-116.

Bifidobacterium breve BR03
4.66 billion CFU
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Studies explore BR03's effect on the prevention and treatment of gastrointestinal disorders, immune modulation and its potential to protect against pathogens.
View Studies
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Solito, A., Bozzi Cionci, N., Calgaro, M., et al. (2021).

Supplementation with Bifidobacterium breve BR03 and B632 strains improved insulin sensitivity in children and adolescents with obesity in a cross-over, randomized double-blind placebo-controlled trial. Clinical Nutrition, 40(7), 4585-4594.

Bifidobacterium lactis BL04
3.25 billion CFU
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This strain has been tested in a broad range of areas, including improving intestinal barrier function, regulating immune defence, reducing the incidence of diarrhoea and associations with the gut-brain axis.
View Studies
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Wang Y, Li N, Yang J.J. et al. 2020.

Probiotics and fructo-oligosaccharide intervention modulate the microbiota-gut brain axis to improve autism spectrum reducing also the hyper-serotonergic state and the dopamine metabolism disorder.

Forssten S.D., Yeung N., Ouwehand A.C. 2020.

Fecal Recovery of Probiotics Administered as a Multi-Strain Formulation during Antibiotic Treatment.

Lactobacillus rhamnosus HN001
1.2 billion CFU
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Lactobacillus rhamnosus HN001 has demonstrated potential to enhance immune function and increase natural cellular immune responses. It has also demonstrated potential to improve skin conditions like eczema.
View Studies
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Barthow, C., Hood, F., Crane, J., et al. (2022).

A randomised controlled trial of a probiotic and a prebiotic examining metabolic and mental health outcomes in adults with pre-diabetes. BMJ Open, 12:e055214.

Bonfrate L, Di Palo DM, Celano G, et al.

Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50(3):e13201.

Bifidobacterium bifidum BB-06
0.88 billion CFU
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Bifidobacterium bifidum BB-06 has been tested mostly around its ability to support the gut-brain axis and gut-skin axis, two growing research areas in gut health.
View Studies
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Ferro, M., Charneca, S., Dourado, E., Guerreiro, C.S., Fonseca, J.E. (2021).

Probiotic Supplementation for Rheumatoid Arthritis: A Promising Adjuvant Therapy in the Gut Microbiome Era. Front. Pharmacol., 12:711788.

Lactobacillus plantarum LP01
0.88 billion CFU
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The literature review of Lactobacillus plantarum LP01 suggests its therapeutic potential in allergies, asthma and autoimmune disorders.
View Studies
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Dr. Narendra Kumar S. 2023.

Lactobacillus plantarum: A Potential Health Booster - A Comprehensive Review.

Bifidobacterium longum BL03
0.88 billion CFU
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Bifidobacterium longum BL03 is a little more limited in its research. However, we have included it in our formulation due to its potential role in immunity and digestion.
View Studies
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Del Piano M., Carmagnola S., Anderloni A. et al. 2010.

The use of probiotics in the treatment of constipation in the elderly.

Lactobacillus acidophilus LA14
0.26 billion CFU
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Lactobacillus acidophilus LA14 has been tested on its role in immune function and modulation, and some limited tests into its ability to improve cognitive function.
View Studies
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De Nunzio, C., Bartoletti, R., Tubaro, A. et al. (2021).

Role of D-Mannose in the Prevention of Recurrent Uncomplicated Cystitis: State of the Art and Future Perspectives. Antibiotics, 10, 373.

+7 more strains
food for your microbiome.
In addition to digestive supplements, a diet rich in fibre and polyphenols is crucial for maintaining a healthy gut.
ready in 25 minutes
pesto butterbeans.

This Pesto Butterbeans recipe is simple, nutritious, and perfect for anyone interested in a gut friendly meal.

ready in 15 minutes
chopped crispy tofu salad with avocado dressing.

Chopped crispy tofu salad with avocado dressing - a balanced blend of flavours and textures, along with gut-friendly ingredients to support your overall well-being.

ready in 10 minutes
carrot cake breakfast oats.

Start your day with a delicious and nutritious breakfast option - Carrot Cake Oats. Filled with fibre diversity to promote healthy digestion.

EXPLORE ALL RECIPES right caret
Emily answers your questions about Epetōme:
The world of supplements and gut health can be confusing. So below I have answered some of your most asked questions.
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What exactly is your microbiome and why is it important?
View Transcript
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When is it appropriate to take a supplement for gut health?
View Transcript
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What can I expect from taking the synbiotic duo cap?
View Transcript
Is the synbiotic duo cap a probiotic?
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The capsule contains live bacteria, therefore it can be considered a probiotic. It also contains fructooligosaccharides (FOS) which can be considered prebiotics. However, we refrain from using such terms as UK Law prevents this, seeing our products as food supplements to which no health claims can be associated.

How long do I need to take the synbiotic duo cap for?
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We recommend taking one capsule a day for a minimum of 3 months. This is how long your microbiome needs to adjust to the new bacteria, as also recommended by the British Society of Gastroenterology to anyone trying a new bacterial product.

Can I take other supplements alongside this for my gut or is Epetōme enough?
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The synbiotic duo cap. has been designed to provide one potent dosage of 50 billion live bacteria in one capsule, from 11 unique strains, alongside other vitamins and minerals that support overall gut health. Therefore as far as live bacteria supplements go, our synbiotic duo cap. should be enough.

What are the active ingredients in the synbiotic duo cap?
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Our capsule combines live bacteria with other vitamins and minerals for added digestive value. See the full nutritional information table for more information:

What are the active ingredients in the synbiotic duo cap?
Are there any side effects from taking the synbiotic duo cap?
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Our gut microbiome is as unique as our fingerprint, therefore your experience with our products will be unique to you. Whilst there should be no adverse effects, some people have reported experiencing an upset stomach, gas, diarrhea, or bloating. Those symptoms usually go away after your body gets used to the bacteria in the synbiotic duo cap (usually within 1-4 weeks). However, if the problem persists, please stop taking immediately and consult your GP.

Other than my gut, will I find any other benefits from taking Epetōme?
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Epetōme is officially classed as a food supplement by UK law, and therefore we cannot legally claim specific health benefits ourselves. We encourage you to do your research.

Our Research Library contains a whole host of studies conducted on the ingredients within our capsule.

RESEARCH LIBRARY >

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What exactly is your microbiome and why is it important?
What exactly is your microbiome? It's a complex community of over 38 trillion microorganisms living in and on your body. Interestingly, there are more microbes than there are human cells in your body. So it is important that we look at our microbiome, as it affects everything from digestion to the immune system, hormones, skin health, and mental well-being. Each of these connections is vital. For instance, the gut-brain axis can influence mood and cognitive function, while gut microbes can impact skin health, digestion efficiency, immunity, and hormonal balance.
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When is it appropriate to take a supplement for gut health?
While a balanced diet is critical to good health, there are times when supplements can play a vital role in maintaining gut health. Let's explore why? It's important to understand how sensitive our gut microbiome is to various lifestyle factors. Our daily choices – what we eat, our stress levels, sleep patterns, and even our physical activity – can significantly impact the balance of our gut. Supplements can fill nutritional gaps, especially in today's fast-paced world, where eating a perfect diet is only sometimes feasible. They can support our digestive health and ensure we have everything to function optimally.
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What can I expect from taking the synbiotic duo cap?
Our carefully designed supplements can lead to various changes in your digestive system over time. We only use high-quality live cultures backed by credible science in state-of-the-art encapsulation to bring you a product you can trust. In the first few days, your body starts getting acquainted with these new guests. It's a time of gentle adjustment. I encourage you to allow your body to get used to the shift. Over the first month, you might notice changes in your digestive routine. It's your body naturally responding to your diet. By 3 months in, your body will adapt and find tempo and balance. Epetome is best taken on an ongoing basis as part of a daily health regime, making sustainable gut health habits an effortless part of your daily routine. Remember, your journey is as unique as you are. It's about consistently nourishing the friendly bacteria in our guts regularly.
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